Bo MA

    mabo@qibebt.ac.cn

    Ph.D., Professor

    Microfluidics System Group

    Group Leader




     

    Education and working experiences: 

    2018-2021 General grant, National Science Foundation of China

    “Microdroplet-MALDI-TOF for bacteria identification”, PI, 0.8M for 4 yrs

    2018-2019 Scientific Instrument Development Program, CAS, PI, 2.9M for 2 yrs

    2015-2018 General grant, NSFC, “Microfluidic-based Raman activated cell sorter”, PI, 0.8M

    for 4 yrs

    2014-2017 Scientific Instrument Development Program, NSFC,“ Instrument development of

    Single-cell Genetic Analyzer”; Co-PI; RMB 3.0M for 4 yrs

    2016-2018 Science and Technology Service (STS) Network Program, CAS,“ Science and

    Technology Service Network for high-throughput Biological Analysis”; Co-PI;

    RMB 2.5M for 3 yrs

    2012-2014 Scientific Instrument Development Program, CAS, “Development of instrument

    for single cell genomics and cultivation”; Co-PI; RMB2.3M for 2 yrs 

    Since 2015.1 Professor. Single Cell Center, QIBEBT, CAS,China
    2012.8-2014.2 Associate Professor, QIBEBT, CAS, China
    2010.12-2012.7 Post Doc, Rice University, USA
    2009.7-2010.11 Post Doc Texas A&M, USA
    2008.6-2009.6 Post Doc, UCLA, USA
    2003.9
    2008.5 Ph.D. in analytical chemistry, Dalian Institute of Chemical Physics, CAS,China,
    1998.9
    2001.7 M.Sc. in analytical chemistry, Sichuan University, China,
    1994.9
    1998.7 B.Sc. in chemistry, China West Normal University, China


    Research interests:

    Microfluidic (lab on a chip) single cell technologies, Biosensor, Microbiome

     

    Publication:     

    1) Xixian Wang#, Lihui Ren#, Yetian Su, Yuetong Ji, Yaoping Liu, Chunyu Li, Xunrong Li, Yi Zhang, Wei Wang, Qiang Hu, Danxiang Han, Jian Xu, Bo Ma, Raman-Activated Droplet Sorting (RADS) for Label-Free High-Throughput Screening of Microalgal Single-Cells,Anal chem, 2017, 89(22): 12569-12577.

    2) Qiang Zhang,Tingting Wang, Yetian Su,Menglong Yang, Jian Xu, Bo Ma, Development of a facile droplet-based single-cell isolation platform for cultivation and genomic analysis in microorganisms. Sci Rep, 2017, 7:41192, DOI: 10.1038/srep41192 

    3) Jian Xu,Bo Ma, Xiaoquan Su, Shi Huang, Xin Xu, Xuedong Zhou, Wei Huang, Rob Knight, Emerging trends for microbiome analysis: from single-cell functional imaging to microbiome big data, Engineering, 2017. 3: 66–70.

    4) Peiran Zhang Lihui Ren Xu Zhang Yufei Shan Yun Wang Yuetong Ji, Huabing Yin, Wei E. Huang,  Jian Xu, Bo Ma,Raman Activated Cell Sorting Based on Dielectrophoretic Single-cell Trap and Release, Anal Chem., Anal Chem. 2015, 87(4):2282-9

    5) P., Liu, Y., Cao, S., Zhang, X., Liu, H., Shi, K., Hu, G., Zhu,B., Ma, H., Niu, A bladder cancer microenvironment simulation system based on a microfluidic co-culture model,Oncotarget. 2015, 6(35):37695-705

    6) Qiang Zhang, Chunbo Mou, Peiran Zhang, Honglei Gou, Zhongyi Zhang, Wei E. Huang, Menglong Yang, Jian Xu and Bo Ma: Towards High-throughput Microfluidic Raman-activated Cell Sorting, Analyst, 2015, 140(18). Analyst, 2015,140, 6163-6174

    7) Qiang Zhang,Peiran Zhang, Yetian Su,..Bo Ma, On-demand control of microfluidic flow via apillary-tuned solenoid microvalve suction, Lab Chip, 2014, 14 (24), 4599 -46031, (cover page)

    8) Chunyu Li, Jian Xu, Bo Ma,Precise quantitative addition of multiple reagents into droplets in sequence using glass fiber-induced droplet coalescence, Analyst, 2015,140, 701-705

    9) Nguyen-Huu TD, Gupta C, Ma B, Ott W, Josic K & Bennett MR, Timing and variability of galactose metabolic gene activation depend on the rate of environmental change. PLoS Comp. Biol. 2015, 11(7): e1004399.

    10) Chunyu Li, Jian Xu, Bo Ma, A self-powered microfluidic monodispersed droplet generatorwith capability of multi-sample introduction,Microfluid Nanofluid,2015, 18:1067–1073

    11) C. Koo, M. Malapi-Wight, H. S. Kim, O. S. Cifci, V. L. Vaughn-Diaz, B. Ma, S. Kim, H. Abdel-Raziq, K. Ong, Y. -K. Jo, D. C. Gross, W. -B. Shim, and A. Han, Development of a Real-Time Microchip PCR System for Portable Plant Disease Diagnosis,PLoS ONE, 2013, Vol. 8 (12), e82704

    12) Bo Ma, Guohao Zhang, Jianhua Qin and Bingcheng Lin, Characterization of drug metabolitesand cytotoxicity assay simultaneously using an integrated microfluidic device, Lab Chip,2009, 232–238

    13) Bo Ma, Dai,Jianhua Qin,Bingcheng Lin, Integrated isotachophoretic preconcentration withzone electrophoresis separation on a quartz microchip for UV detection of flavonoids,Electrophoresis2006, 27,4904–4909

    14) Bo Ma, Xiaomian Zhou, Gang Wang, Jianhua Qin, Bingcheng Lin, A hybrid microdevice with a thin PDMS membrane on the detection window for UV absorbance detection,Electrophoresis, 2007, 28, 2474‐2477


    Patents:

    1) Chunyu Li,  Bo Ma , Jian Xu, A self-powered  droplet generator  CN, ZL201310382774.0,  Issue date: 2016 2016-03 -09
    2) Chunyu Li, Bo Ma , Jian Xu, Fiber-Induced Droplet Coalescence on the microfluidic chip chip, CN, ZL201410167135.7, Issue date: 2016 -11 -23
    3) Lihui Ren, Kang Ning, Bo Ma , Jian Xu, Wei Huang,, Raman activated Single cell sorting controller CN, ZL201210567603.0,Issue date: 2016 -08 -10
    4) Bo Ma, Peiran Zhang, Jian Xu, DEP single cell trap/release for Raman Activated Cell Sorting, CN, ZL 201310613921.0, Issue date: 2017.11.28 

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